Department of Orthopaedic Surgery

MechanoBiology Laboratory receives DOD-MTEC Award

Dr. James Wang, Director of the MechanoBiology Laboratory, received a DOD-MTEC grant award.

Project title:  Repurposed Metformin as a Preventative Therapeutic for Tendon Overuse Injuries
Project Period:  10/01/22 – 09/30/24
Total Award Amount:  $2,848,397

This study aims to collect the efficacy, pharmacokinetics, and safety/toxicity data of metformin (Met) on the prevention of tendinopathy in animal models with the goal to submit an IND application to FDA and get the regulatory approval.